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Research Update – Why Cavernomas cause seizures or strokes

Researchers have discovered an explanation for why cavernoma – clusters of dilated blood vessels in the brain – can suddenly grow to cause seizures or stroke. Specifically, they found that a specific, acquired mutation in a cancer-causing gene (PIK3CA) could exacerbate existing cavernoma in the brain. Furthermore, repurposing an already existing anticancer drug showed promise in mouse models of cavernoma in improving brain-vascular health and preventing bleeding into the brain tissue.

David White will be discussing this further at his The Science of Cavernoma webinar at 7 p.m. next Thursday 6th May 2021. Register at events@cavernoma.org.uk

For more information, please see the article; https://www.nih.gov/news-events/news-releases/cancer-linked-mutation-accelerates-growth-abnormal-stroke-causing-brain-blood-vessels